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Home/ Products & Services/Supplements / EpiCor® Postbiotic
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EpiCor fermentate - Cargill bulk ingredient supplier for immune support.

EpiCor® Postbiotic

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What is EpiCor?

EpiCor® is an innovative, science-backed postbiotic ingredient clinically shown to support immune health. Derived from the fermentation of Saccharomyces cerevisiae (baker’s yeast), EpiCor® contains a beneficial mix of metabolites and numerous other health-enhancing bioactive compounds. This complex ingredient has an epic origin story and a track record of success as the focus of more than 15 published studies. Trusted globally, EpiCor® is also the #1 postbiotic ingredient, having been formulated into more products than any postbiotic on the market!

*The ISAPP consensus definition and scope for postbiotics, which EpiCor adheres to fully, is: “A preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”.

 
 

How It’s Different

#1 Postbiotic Ingredient #1 Postbiotic Ingredient* - Trusted by a multitude of top supplement brands and health enthusiasts the world over, EpiCor has been integrated into more dietary supplement products than any other postbiotic. For us, being #1 is not just a claim, it’s simply who we are.
 

15 Published Studies 15 Published Studies – Experience the power of science with EpiCor. Clinically shown to support immune health and positively modulate the gut microbiome; the benefits are backed by research. In an industry where science is the cornerstone, we are proud to hold the key to innovation.
 

75 Years of Fermentation Expertise 75 Years of Fermentation Expertise – Leverage a proven history of experience and reliability. From its serendipitous discovery to 75 years of fermentation expertise, our journey is a testament of turning observation into a time-tested commitment to excellence.

*According to the Innova New Products Database, published by Innova Market Insights, October 2023. 

 

 

EpiCor Postbiotic

Learn more about the ingredient clinically shown to support immune health.

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Epic Origin

Factory workers were taking fewer sick days than colleagues. A pilot study found exposure to the product was supporting their immune health, and EpiCor was born.

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Complete Postbiotic

Through proprietary fermentation outside of the body, EpiCor postbiotic consistently delivers the right, beneficial mix of metabolites directly to the host.

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Formulation & Application

Experience versatility and simplicity with EpiCor. As a highly stable ingredient, EpiCor can be easily formulated into Dietary Supplements, Adult Nutrition offerings, or even Pet Food, Treats, and Supplements.

  • Inanimate yet Effective – Experience simplicity without compromising efficacy. As an inanimate ingredient, EpiCor offers increased stability and consistency as compared to more familiar immune ingredients such as probiotics.
  • Low Dose Benefits – Redefine effectiveness with EpiCor, an ingredient clinically studied at a daily dose of only 500mg.
  • Extensive Shelf-life - Enjoy longevity without compromise. EpiCor offers a three-year shelf life from date of manufacture
  • Certified Quality - EpiCor maintains certifications that speak volumes about quality and transparency. Made in the USA, EpiCor has earned certifications and designations including: Non-GMO Project Verified, NSP Certified, FDA GRAS No Objection, Certified Halal, Certified OU Kosher, Vegan/Vegetarian, Gluten Free, and TSE/BSE Free.

Epicor Formulation & Application




EpiCor Research:

  • Winter Trials for Immune Support
  • Spring Trial for Immune Support
  • Rapid Response Trial for Immune Support
  • Other Trials for Immune Support
  • Preclinical Study for Immune Support
  • Trial for Gut Support
  • Preclinical Trials for Gut Support

Human Clinical Trials: Winter Immune Support

1. Moyad, M. A.,  et al. Effects of a modified yeast supplement on cold/flu symptoms. Urol Nurs 2008, 28 (1), 50-5.

Read the abstract

2. Moyad, M. A., et all.  Immunogenic yeast-based fermentate for cold/flu-like symptoms in nonvaccinated individuals. J Altern Complement Med 2010, 16 (2), 213-8.  

Read the abstract

 

 

EpiCor Postbiotic Research Study - EpiCor Impacts Cold and Flu Symptoms on Healthy Adults

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Human Clinical Trials: Spring Immune Support

Moyad, M. A., et al. Immunogenic yeast-based fermentation product reduces allergic rhinitis-induced nasal congestion: a randomized, double-blind, placebo-controlled trial. Adv Ther 2009, 26 (8), 795-804. 

Read the abstract

 

 

 

EpiCor Research Study - Effects on Seasonal Allergies

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Human Clinical Trials: Rapid Immune Response

Jensen, G. S., et al.  Antioxidant bioavailability and rapid immune-modulating effects after consumption of a single acute dose of a high-metabolite yeast immunogen: results of a placebo-controlled double-blinded crossover pilot study. J Med Food 2010, 14, 1002–1010. 

Read the abstract

 

 

EpiCor Research Study - Rapid Immune-Modulating Effects of EpiCor on Adults

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Human Clinical Trials: Other Immune Support

1. Jensen, G. S., et al.  A double-blind placebo-controlled, randomized pilot study: consumption of a high-metabolite immunogen from yeast culture has beneficial effects on erythrocyte health and mucosal immune protection in healthy subjects. Open Nutr J 2008, 2, 68-75. 

Read the abstract

2. Jensen, G. S., et all.  Anti-inflammatory properties of a dried fermentate in vitro and in vivo. J Med Food 2014, 18(3), 378-84. 

Read the abstract

 

 

Preclinical Trial: Immune Support

Jensen, G. S.,  et al. An anti-inflammatory immunogen from yeast culture induces activation and alters chemokine receptor expression on human natural killer cells and B lymphocytes in vitro. Nutrition Research 2007, 27, 327-335. 

Read the abstract

 

 

 

Human Clinical Trial: Gut Support

Pinheiro, I., et al. A yeast fermentate improves gastrointestinal discomfort and constipation by modulation of the gut microbiome: results from a randomized double-blind placebo-controlled pilot trial. BMC Complement Altern Med 2017, 17 (1), 441. 

Read the abstract

 

 

 

EpiCor Research Study - Effects on Gastrointestinal  Comfort and Gut Microbiome Levels

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Preclinical Trials: Gut Support

1. Possemiers, S., et al.  A dried yeast fermentate selectively modulates both the luminal and mucosal gut microbiota and protects against inflammation, as studied in an integrated in vitro approach. J Agric Food Chem 2013, 61 (39), 9380-9392. 

Read the abstract


2. Marzorati, M., et al.  The HMI module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro. BMC Microbiol 2014, 14 (1), 133. 

Read the abstract



3. Durcray, H.A.G., et al.  Mitigation of heat stress-related complications by a yeast fermentate product. Jl Therm Bio 2016 , 60,26–32. [Online reference: https://www.ncbi.nlm.nih.gov/pubmed/27503713]

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4. Ducray, H.A.G., et al. Yeast fermentate prebiotic improves intestinal barrier integrity during heat stress by modulation of the gut microbiota in rats. J  Appl Microbiol 2019, 127, 1192—1206. [Online reference: https://www.ncbi.nlm.nih.gov/pubmed/31230390]

Read abstract

 

 

 

Some Cargill products are only approved for use in certain geographies, end uses, and/or at certain usage levels. It is the customer's responsibility to determine, for a particular geography, that (i) the Cargill product, its use and usage levels, (ii) the customer's product and its use, and (iii) any claims made about the customer's product, all comply with applicable laws and regulations.

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