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Check out our FAQs to learn more about EpiCor® postbiotic. If you don’t find what you’re looking for, contact us and we’ll be happy to help. 

What is EpiCor® postbiotic?

EpiCor® postbiotic is a whole food fermentate resulting from a proprietary anaerobic fermentation using Saccharomyces cerevisiae (baker’s yeast). It is comprised of a unique fingerprint of metabolites that supports immune and gut health. Published studies show that EpiCor® postbiotic supports the immune and digestive systems for better overall health and wellness. In other words, EpiCor acts like a multivitamin for your immune system®

Who makes EpiCor® postbiotic?

Cargill Health Technologies produces EpiCor® postbiotic fermentate in its dedicated state-of-the-art manufacturing facility in Ankeny, Iowa USA. EpiCor® postbiotic is produced under dietary ingredient cGMP conditions and certified by NSF International (21 C.F.R. Part 111 [“Dietary Supplements”]). Other attributes include: Non-GMO Project Verification, kosher by the Orthodox Union, halal,FDA GRAS no objection and FDA New Dietary Ingredient (NDI) Notification submitted. 

What does EpiCor® postbiotic do for immune health? 

Over a dozen published human clinical and preclinical trials show EpiCor® postbiotic supports immune strength. More specifically, EpiCor® postbiotic has been shown to support year-round respiratory health.

What does EpiCor® postbiotic do for gut health? 

Multiple published studies show that EpiCor® postbiotic is a whole food fermentate that supports gut health, which in turns supports immune health. It has been clinically shown to promote healthy human gut ecology and positively modulates the gut microbiome.    

How does it work?

EpiCor® postbiotic is made through the natural process of fermentation that supports a healthy gut microbiome which, as ongoing research suggests, helps to support a healthy immune system. It’s rich with metabolites and when taken daily acts like a vitamin for your immune system®. EpiCor® postbiotic helps people live more healthy days™ by: 

  • Maintaining daily immune health 
  • Supporting nasal comfort 
  • Positively modulating the gut microbiota


What is a postbiotic?

According to the International Scientific Association for Probiotics and Prebiotics (ISAPP), the scope and definition for postbiotics is: Postbiotics are functional compounds and metabolites produced by microorganisms like yeast and bacteria during a fermentation process. Postbiotics include microbial cells and cell constituents. EpiCor® postbiotic is made through a specialized fermentation process that creates a unique fingerprint of metabolites. It is the most researched postbiotic ingredient that supports immune and gut health benefits.  


What’s the difference between postbiotics, probiotics and prebiotics? 

Here is a simple analogy that might help to explain the differences: 

  • The Fuel: Prebiotics are the food for the beneficial bacteria to conduct fermentation in the gut (fuel for the factory).  
  • The Factory Workers: Probiotics are live microorganisms that can do the fermentation to create beneficial metabolites.  
  • The Goods: Postbiotics are those beneficial metabolites (the good stuff that comes out of the factory). Postbiotics can be created within or outside of the human body.  



What advantages does EpiCor® postbiotic have over other gut or immune health ingredients? 

EpiCor® postbiotic is a one-of-a-kind, whole food fermentate clinically shown to support immune and gut health. It is one of the most clinically researched ingredients shown to maintain immune support and positively modulate the gut microbiota. EpiCor® postbiotic is not extracted, purified or one single compound. It is comprised of a unique fingerprint of metabolites that altogether have been shown to support immune and gut health. Inspired by a real-life health discovery and backed by clinical research, EpiCor is one of the first postbiotic fermentates shown to help people live more healthy days™.


What are the advantages of postbiotics?

Within your gut, the fermentation process that happens when the bacteria ingest the prebiotics can cause bloating. With postbiotics like EpiCor® postbiotic that are made outside of the human body, there are fewer side effects such as bloating or overall digestive discomfort. EpiCor® postbiotic also has over a dozen of published trials showing that it supports the immune system and gut microbiome.  



Does EpiCor® postbiotic have an NDI on file with the FDA?  

A New Dietary Ingredient (NDI) notification was successfully submitted to the FDA for EpiCor® postbiotic. Manufacturers can have the peace of mind knowing that choosing EpiCor® postbiotic means being in full compliance with the Federal Food, Drug, and Cosmetic (FD&C) Act pertaining to new ingredients introduced into the marketplace after October 14, 1994.


Is EpiCor® postbiotic safe?  

Yes, EpiCor is GRAS (Generally Recognized As Safe) for use in most foods or beverages for ages 2 years and older.  For supplements, EpiCor is recommended for ages 4 years and older. The U.S. Food and Drug Administration (FDA) responded with a letter of no objection to Cargill’s GRAS notification for EpiCor® postbiotic use in certain foods and beverages. Also, the science substantiating EpiCor® postbiotic’s safety was published in the peer-reviewed International Journal of Toxicology. 


What is the efficacious dose of EpiCor® postbiotic for adults?  

All of the published human clinical trials were conducted with healthy adults consuming a daily dose of 500 mg of EpiCor® postbiotic.

What is the safe, maximum dose of EpiCor® postbiotic for adults and children?  

In the US there are different dose and age recommendations for dietary supplements and food use because of the differences in the US regulatory pathways for foods and supplements. For dietary supplements, a daily consumption of 3,000 mg of EpiCor® postbiotic is acceptable for adults and 500 mg of EpiCor® postbiotic for children over the age of four years old per levels presented in the EpiCor® New Dietary Ingredient Notification NDIN 689. For food products, a dose of 500mg per serving of EpiCor® postbiotic is acceptable for ages two and older, based on the intended use categories evaluated in Generally Recognized as Safe Notice GRN 928 and Cargill’s GRAS self-determination.

In the EU, EpiCor® postbiotic was determined to not be a novel food by the Food Safety Authority of Ireland.



How can EpiCor® postbiotic be identified on a product label?   

The common and usual name for EpiCor® postbiotic is “dried fermentate (made using Saccharomyces cerevisiae).” Reach out to our sales team at [email protected] to find out how EpiCor® postbiotic's identity is registered outside the USA.


Is EpiCor® postbiotic a beta glucan?  

No, EpiCor® postbiotic is not a beta glucan. EpiCor® postbiotic is a whole food fermentate resulting from a natural microbial fermentation. It is composed of a unique fingerprint of metabolites with 1,3 1,6 beta glucan being just one of the many components.


Can EpiCor® postbiotic safely be combined with other ingredients in formulations?   

Yes, EpiCor® postbiotic is perfectly suited for formulation with other ingredients that may complement the benefits of EpiCor® postbiotic. This was confirmed in the NDI Notification and GRAS determination. 

Can EpiCor® postbiotic be combined with probiotics? 

Yes. With a low active water level of <.3, EpiCor® postbiotic is has been successfully formulated with probiotics.  

What product delivery forms are possible with EpiCor® postbiotic? 

EpiCor® postbiotic has been successfully formulated into two-piece, hard-shell capsules, ingestible tablets, time-release tablets, chewable tablets, soft-gels, dry powders, effervescent powders and wafers, concentrated drink mixes, RTD beverages, 1 and 2 oz “shots”, gummies, soft chews, and lozenges. Cargill’s application and quality departments have experience formulating EpiCor® postbiotic into new product forms and confirming stability.   

Where throughout the world is EpiCor® postbiotic registered?

EpiCor® postbiotice has a suitable regulatory status for most major important markets throughout the world. Please reach out to our sales team at [email protected] to find out if EpiCor® postbiotic is registered in your country.

Is EpiCor® postbiotic heat stable? 

EpiCor® postbiotic is heat and pressure stable under conditions normally found in food and beverage processing. 

Does EpiCor® postbiotic have a flavor?

EpiCor® postbiotic has a naturally pleasant, savory aroma and flavor. In addition, it has been successfully flavor-masked and formulated into certain beverages, chewable tables, dry drink mixes, gummies, soft chews and lozenges. 

Is EpiCor® postbiotic soluble? 

EpiCor® postbiotic is dispersible but only partially soluble.  

Is private labeling available for EpiCor® postbiotic? 

Yes. Please reach out to our sales team at [email protected] for more information.