Differentiate with EpiCor® Postbiotic
- Clinically Researched. Over a dozen published studies, including multiple clinical human trials, show that it helps support the immune system, nasal comfort and positively modulate the gut microbiome.
- #1 Postbiotic Brand1. Postbiotics is an emerging, new health ingredient that consumers are excited about and with our investment in consumer marketing and supporting our customers products, EpiCor® is the leading postbiotic brand.
- Easy to Formulate. EpiCor® postbiotic is PH and heat stable making it suitable for many applications.
- Label-Friendly. Made in the USA, EpiCor® postbiotic is label-friendly with certifications and designations such as Non-GMO Project Verified, FDA GRAS no objection, vegan/vegetarian, gluten free, kosher, halal and BSE/TSE free.
1. According to Innova Data (July 2021).
What is EpiCor®?
As the #1 postbiotic brand, EpiCor® postbiotic is a whole food fermentate clinically shown to support immune and gut health. It’s made through a specialized fermentation process that creates a unique fingerprint of metabolites including proteins, peptides, antioxidants, polyphenols, organic acids, nucleotides, polysaccharides (1-3 1-6, beta glucans) and mannans. When taken daily, EpiCor® postbiotic acts like a multivitamin for the immune system®.
What are Postbiotics?
The ISAPP consensus definition and scope for probiotics is: “A preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”. EpiCor® postbiotic is a non-living composition of metabolites and functional compounds that have been shown in over a dozen published studies to support immune and gut health.
Postbiotics vs. Pre- & Probiotics
Learn about a new health category that is revolutionizing the immune and gut health space.
Next Evolution in Immune and Gut Health: Postbiotics
Learn about how Cargill's Health Technology business is a leader in postbiotic technology.
What's the Difference? Prebiotics, Probiotics & Postbiotics
This infographic helps easily explain what makes postbiotics unique.
Origin: A Real-Life Health Discovery
In the late 1800’s C.W. Bloomhall, a young boy who lived on a family farm, noticed that animals fed table scraps fermented with sour milk seemed to be healthier than animals fed simple grains alone.
After retiring from the milling industry in 1943, Bloomhall decided to put his theory to the test – that fermented foods provided unique health benefits. He founded the Diamond V® company to develop a specialized fermentation process to create an ingredient that would improve the health and productivity of livestock.
The Diamond V brand is now owned by Cargill and a highly respected brand of unique microbial fermentation products for improved animal health worldwide.
Fast forward to 1998: EpiCor’s Discovery
Factory employees at Diamond V’s manufacturing facility who were exposed daily to the fermented animal feed were not using much sick leave.
Why were the factory workers taking fewer sick days than their colleagues working in the office? To find out, Diamond V commissioned pilot studies comparing the factory workers to a similar group of office workers. And, those studies showed the fermented product had supported the immune health of the factory workers that were exposed.
After years of clinical research to show the safety and efficacy in people, EpiCor® postbiotic was born! Today, people all around the world trust EpiCor® postbiotic to support their immune and gut health.
How It's Made
Made in in the USA, EpiCor® postbiotic is made in a state-of-the-art facility that follows all current Good Manufacturing Processes (cGMP) certified by NSF. It is made through a specialized fermentation process that creates a unique fingerprint of metabolites and functional compounds consisting of proteins, peptides, antioxidants, polyphenols, organic acids, nucleotides, polysaccharides (1-3 1-6, beta glucans, and mannans).
To make EpiCor®, we start with baker’s yeast, Saccharomyces cerevisiae, and feed it a proprietary broth of natural, plant-based ingredients. It then goes through a specialized fermentation process where the yeast is deprived of oxygen, which causes them to produce beneficial metabolites.
The final production step uses a proprietary and gentle drying process that deactivates the yeast (there are NO live yeast or other organisms in EpiCor® postbiotic) and preserves the complex array of metabolites created during fermentation. EpiCor® postbiotic is considered a “whole food” fermentate because nothing is extracted or purified - we use the whole fermentation broth and gently dry it to a powder. The dehydrated whole food fermentate is then milled to a fine powder and packaged within containers designed to protect it during storage and handling.
Following extensive safety and identity testing, the result is EpiCor® postbiotic – a whole food yeast fermentate that helps support the immune system and positively modulate the gut microbiome.
How it Works
Over a dozen published studies show that EpiCor® has a wide range of real-life health benefits. These studies show EpiCor® supports a strong immune system and healthy gut to help people live more healthy days™. EpiCor® postbiotic:
• Maintains daily immune health
• Supports year-round nasal comfort
• Positively modulates the gut microbiome
• Supports digestive health
Made through a natural fermentation process, EpiCor® postbiotic supports a healthy gut microbiome which, as ongoing research suggests, helps to support a healthy immune system. It is rich with metabolites and when taken daily acts like a vitamin for your immune system™.
Versatility is one of the key advantages of postbiotics; they offer increased stability and consistency as compared to the more familiar ingredients like probiotics. Probiotics are inherently harder to work with than metabolites in postbiotics because they must remain alive – from processing and packaging until they reach the consumer’s gut.
EpiCor® postbiotic is well-suited to a wide range of food and beverage applications. It is not a living organism and is highly heat stable. In addition, EpiCor® postbiotic can handle varying pH levels and has a three-year shelf life from its manufacture date.
EpiCor Research: Immune and Gut Support
- Winter Trials for Immune Support
- Spring Trial for Immune Support
- Rapid Response Trial for Immune Support
- Other Trials for Immune Support
- Preclinical Study for Immune Support
- Trial for Gut Support
- Preclinical Trials for Gut Support
Human Clinical Trials: Winter Immune Support
1. Moyad, M. A., et al. Effects of a modified yeast supplement on cold/flu symptoms. Urol Nurs 2008, 28 (1), 50-5.
2. Moyad, M. A., et all. Immunogenic yeast-based fermentate for cold/flu-like symptoms in nonvaccinated individuals. J Altern Complement Med 2010, 16 (2), 213-8.
Human Clinical Trials: Spring Immune Suppport
Moyad, M. A., et al. Immunogenic yeast-based fermentation product reduces allergic rhinitis-induced nasal congestion: a randomized, double-blind, placebo-controlled trial. Adv Ther 2009, 26 (8), 795-804.
Human Clinical Trials: Rapid Immune Response
Jensen, G. S., et al. Antioxidant bioavailability and rapid immune-modulating effects after consumption of a single acute dose of a high-metabolite yeast immunogen: results of a placebo-controlled double-blinded crossover pilot study. J Med Food 2010, 14, 1002–1010.
Human Clinical Trials: Other Immune Support
1. Jensen, G. S., et al. A double-blind placebo-controlled, randomized pilot study: consumption of a high-metabolite immunogen from yeast culture has beneficial effects on erythrocyte health and mucosal immune protection in healthy subjects. Open Nutr J 2008, 2, 68-75.
2. Jensen, G. S., et all. Anti-inflammatory properties of a dried fermentate in vitro and in vivo. J Med Food 2014, 18(3), 378-84.
Preclinical Trial: Immune Support
Jensen, G. S., et al. An anti-inflammatory immunogen from yeast culture induces activation and alters chemokine receptor expression on human natural killer cells and B lymphocytes in vitro. Nutrition Research 2007, 27, 327-335.
Human Clinical Trial: Gut Support
Pinheiro, I., et al. A yeast fermentate improves gastrointestinal discomfort and constipation by modulation of the gut microbiome: results from a randomized double-blind placebo-controlled pilot trial. BMC Complement Altern Med 2017, 17 (1), 441.
Preclinical Trials: Gut Support
1. Possemiers, S., et al. A dried yeast fermentate selectively modulates both the luminal and mucosal gut microbiota and protects against inflammation, as studied in an integrated in vitro approach. J Agric Food Chem 2013, 61 (39), 9380-9392.
2. Marzorati, M., et al. The HMI module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro. BMC Microbiol 2014, 14 (1), 133.
4. Ducray, H.A.G., et al. Yeast fermentate prebiotic improves intestinal barrier integrity during heat stress by modulation of the gut microbiota in rats. J Appl Microbiol 2019, 127, 1192—1206. [Online reference: https://www.ncbi.nlm.nih.gov/pubmed/31230390]
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